J Bone Jt Infect 2019; 4(3):115-119. doi:10.7150/jbji.34679

Case Report

Marjolin's Tumor Complicating Chronic Periprosthetic Infection of a Total Knee Arthroplasty

Timothy Horan1, Matthew T. Wallace2✉, Albert J. Aboulafia2, Janet D. Conway3

1. Philadelphia College of Osteopathic Medicine Orthopaedic Surgery, Philadelphia, PA
2. MedStar Georgetown Cancer Institute, National Center for Bone and Soft Tissue Tumors, MedStar Franklin Square Medical Center
3. Rubin Institute for Advanced Orthopaedics, Baltimore, MD

Abstract

Marjolin's tumor is a term used to describe a malignancy developing in the setting of a chronic wound, infection, or other tissue subject to chronic inflammatory changes. These malignancies usually present after many years of chronicity, and can range from lower grade basal cell carcinomas to high-grade sarcomas. We present the case of a squamous cell carcinoma that developed within a chronic periprosthetic infection of a total knee arthroplasty of 7 years duration. The intra-articular location, association with an orthopaedic implant, and brief latency period are all unique features of this case.

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How to cite this article:
Horan T, Wallace MT, Aboulafia AJ, Conway JD. Marjolin's Tumor Complicating Chronic Periprosthetic Infection of a Total Knee Arthroplasty. J Bone Jt Infect 2019; 4(3):115-119. doi:10.7150/jbji.34679. Available from http://www.jbji.net/v04p0115.htm