J Bone Jt Infect 2017; 2(1):29-37. doi:10.7150/jbji.16067

Review

Therapeutic Use of Antibiotic-loaded Bone Cement in the Treatment of Hip and Knee Joint Infections

Konstantinos Anagnostakos

Zentrum für Orthopädie und Unfallchirurgie, Klinikum Saarbrücken, Saarbrücken, Germany.

Abstract

The use of antibiotic-loaded cement spacers is an established method in the management of periprosthetic hip and knee joint infections. Despite inconsistencies among published studies, data shows that infection control rates exceed 90% with two-stage exchange arthroplasty. The present work reviews the current literature about antibiotic-loaded cement spacers and concentrates on the indications for spacer implantation, spacer production details, antibiotic impregnation, pharmacokinetic properties, clinical success, mechanical complications, and systemic safety.

Keywords: hip spacer, knee spacer, hip infection, knee infection, antibiotic-loaded bone cement.

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How to cite this article:
Anagnostakos K. Therapeutic Use of Antibiotic-loaded Bone Cement in the Treatment of Hip and Knee Joint Infections. J Bone Jt Infect 2017; 2(1):29-37. doi:10.7150/jbji.16067. Available from http://www.jbji.net/v02p0029.htm